John Harvey Kellogg was a leading advocate for the basis of autointoxication and, the legend goes, manufactured whole-grain cereals to promote regular bowel movements. http://www.cleansercolon.com (It was his brother, Will, who founded the Assault Creek Toasted Corn Flake Company, which later became the Kellogg Company.)
His book, Colon Health, Emphasizes prevention but also promises relief from these afflictions: constipation, fatigue, poor eyesight, hearing loss, asthma, prostate trouble, colds, allergies, nagging backache, respiratory disorders, digestive problems, gas, abdominal pain, colitis, thyroid deficiency, diabetes, and jillion other aliments.